Did you know…  Probiotics help keep a healthly intestinal tract. Customer reviews…  for many years I'm a satisfacted customer,thank you bigvits! christine/italy

Shopping cart

Your cart will appear here when items are selected for purchase.

Product
Search

A-Z Products Index

*Vitamin B-5, Pantethine, 450mg x 60SGelsJarrow Formulas

Vitamin B-5, Pantethine, 450mg x 60SGels
Pantethine is reported to show very good results in the fight with high readings for cholesterol and triglycerides.


Customer Reviews...

..."Love this product, especially now that it is in the 450 mg...as a cholesterol lowering aid it has been suggested to take 900 mg...and since doing so, my husband has been able to go off the drugs and his numbers are lower then they were when he was on the drugs."

..."I have always taken this but recently i found out it helps with adrenal problems. My husband was always losing it in traffic and any stressful situation. Now that i started giving him this, it has helped tremendously"

..."Good product, great price. Helpful for stress & reducing belly fat."
No product offered for sale is intended to diagnose, treat, cure or prevent any disease. You should always seek advice from your professional healthcare provider before taking any medication. Always read the details and instructions on the label, keep the tub tightly sealed and out of the reach of children.
Product Code: JRW388
SRP £22.45
BigVits Price
£17.95
2 - 2£17.45
3 +£16.95
Best Before
Apr 2019
Shipping Weight
90 g
These are similar products and show possible savings
Jarrow Formulas Vitamin B-5, Pantothenic Acid, 500mg x 100Caps
Saving £10.50
£7.45 Details
Now Foods Vitamin B-5, Pantothenic Acid, 500mg x 250Caps
Saving £3.70
£14.25 Details
Please note:  BigVits do not make any medical suggestion or recommendation as to the suitability of a product.
You must check that similar products are suitable for your situation and if in doubt discuss with your medical advisor.

Product Details

Jarrow Formulas

Pantethine 

450mg x 60 Soft Gels

 Description

  Pantesin

Coenzyme A Precursor

Supports Lipid Metabolism

Dietary Supplement

 Pantethine is a derivative of vitamin B5. Pantethine supports lipid metabolism by its ability to raise levels of CoA, a cofactor involved in several metabolic pathways including carbohydrate and lipid metabolism. CoA combines with acetyl groups to form Acetyl CoA, a participant in energy production.

 Suggested Use

 Take 1 softgel per day with a meal, or as directed by your qualified health care consultant

 

No product offered for sale is intended to diagnose, treat, cure or prevent any disease. You should always seek advice from your professional healthcare provider before taking any medication. Always read the details and instructions on the label, keep the tub tightly sealed and out of the reach of children.

Supplement Facts

 

Supplement Facts

Serving Size: 1 Softgel

Servings Per Container: 60

 

Amount Per Softgel

% DV

Pantethine

450 mg

*

* Daily Value not established.

 Other Ingredients

 Softgel consists of gelatin, glycerin, water, annatto extract and caramel (added as a light barrier).

No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.

 Warnings

 Note: If you are pregnant, lactating, or trying to conceive, consult your health care practitioner before using this product.

 Keep out of the reach of children.

 

 
No product offered for sale is intended to diagnose, treat, cure or prevent any disease. You should always seek advice from your professional healthcare provider before taking any medication. Always read the details and instructions on the label, keep the tub tightly sealed and out of the reach of children.

Testimonials

These testimonials are the personal views of other users and do not represent a medical opinion.

 

Reviews & Testimonials 

Reducing Bad Cholesterol Levels,

from Texas

Love this product, especially now that it is in the 450 mg...as a cholesterol lowering aid it has been suggested to take 900 mg...and since doing so, my husband has been able to go off the drugs and his numbers are lower then they were when he was on the drugs. I might mention that he took cholesterol lowering drugs, including Lipitor, for over 10 years...and now has been off the drugs for over 2 years! 

Jarrow Pantethine,

From Canada

Jarrow's Pantethine is importantly certified under the Japanese Pantesin process controls and guarantees. Watch for more public awareness of this coenzyme, as well as with coenzyme Q10, as statin side-effects become less tolerated. 

Many benefits!,

By Anne Gibson from Michigan

This product has kept me from an expensive cholesterol perscription, for which I am thankful. 

PANTHENINE,

From California

MY HUSBAND'S BAD CHOLESTROL CAME DOWN TO NORMAL AND IT INCREASED THE GOOD CHOLESTROL SO THERE IS A HEALTHY RATIO, THUS REDUCING HIS RISK FOR A HEART ATTACK!

Works for lowering cholesterol,

From Washington

Taking 900 mgs a day of the Jarrow pantenthine (which is derived from the Japanese-made Pantesin product) achieved a nice improvement in my cholesterol numbers. Definitely worth a look if you want an alternative to statin drugs. I also tried policosinol, which proved to be useless. 

Great for Triglyceride reduction,

from Arizona

After on;y 1 month, my triglyceride level was reduced by 40%. Jarrow's formulation is high potency, low cost! 

Belly fat,

from Australia

Good product, great price. Helpful for stress & reducing belly fat. When stressed the adrenals work overtime which often makes it difficult to shed weight especially around midsection.

A wonder supplement,

From New Hampshire

I couldn't believe how dramatic the change this supplement does when I take it with panthothenic acid and b-vitamins. Pantethine helps speed up dramatically with my slow wound healing as well as normalizes my energy production by giving a big boost to my adrenals.

Seeing results after one month,

From Missouri

Doctor wanted me to try statins, had a severe reaction. My numbers are coming down after just one month. Have placed my second order...will continue using hoping for even better results.

take for high cholesterol,

From Illinois

took my 309 high to 224 along w/flaxseed meal...won't ever take any statins thanks to this...

Effective,

From Japan

I had a heart scare about 4 years ago and learnt about Pantethine from Robert Kowalski. I had my blood tested religiously for months while I adjusted my diet and supplementation regimen. The inclusion of Pantethine seemed to significantly lower my triglycerides and there was also a significant rise in my HDL cholesterol. For those of you who are struggling to manage these 2 factors I highly recommend you give Pantethine a try.

Passed Life insurance physical...,

From New Jersey

Due to some 'other stuff' I was taking previously, my LDL was huge, and my HDL was low...and my liver was no prize either, but after a month on this, everything was back in order and I got my LI policy. Will continue to use this from time to time making sure everything is OK.

I have always taken this but recently i found out it helps with adrenal problems,

from Louisiana

I have always taken this but recently i found out it helps with adrenal problems. My husband was always losing it in traffic and any stressful situation. Now that i started giving him this, it has helped tremendously. You have to have more Pantethine than you get in a vitamin B complex. This product works.

  

No product offered for sale is intended to diagnose, treat, cure or prevent any disease. You should always seek advice from your professional healthcare provider before taking any medication. Always read the details and instructions on the label, keep the tub tightly sealed and out of the reach of children.

More Information

 

Quick Reference Guide

 

Pantethine

 

Pantethine is a derivative of vitamin B5 and the stable disulfate form of pantetheine, which provides the active portion of coenzyme A (CoA), a central carrier protein in cellular metabolism.  The actions of vitamin B5, also known as pantothenic acid, require that a cysteamine molecule containing a free sulfhydryl (SH) group be conjugated to pantothenic acid to create the active form.  Pantethine comes ready-made with cysteamine attached and, therefore, is more metabolically active than pantothenic acid.

 

Pantethine is important in the production of CoA, a necessary cofactor in more than 70 distinct biochemical pathways in the body.  These pathways include fatty acid oxidation, carbohydrate metabolism, the synthesis of acetylcholine, and detoxification in the liver.  As an immediate precursor to CoA, pantethine may provide benefits not found with pantothenic acid, which requires enzymatic activation.

 

Coenzyme-A & Lipid Metabolism

 

The actions of pantethine in promoting proper lipid metabolism have not been fully explained, but influence is clearly exerted upon the enzymes involved in cholesterol synthesis and carbohydrate metabolism, since each coenzyme-A molecule is composed of onehalf of a panthethine molecule.  Coenzyme-A acts as an acceptor of acetyl groups produced via pyruvate decarboxylation in the mitochondria forming acetyl-CoA.  Acetyl-CoA then enters the Krebs Cycle, where it provides the substrate for energy production.  Due to this role, acetyl-CoA is essential to the balance between carbohydrate and fat metabolism.

 

Pantethine also may direct the primary precursor of cholesterol toward beta-oxidation (in which fats are burned to produce energy) or into other catabolic, energy-producing cycles.  In fact, one theory holds that the catabolic product of pantethine, cystamine, modulates the activity of hepatic acetyl-CoA carboxylase, leading to increased hepatic oxidation of lipids.

 

Supplementation with pantethine often progressively supports the metabolism of cholesterol, triglycerides, low density lipoprotein (LDL) cholesterol and apolipoprotein B (Apo-B) while leading to support for healthy levels of high density lipoprotein (HDL) cholesterol and apolipoprotein A (Apo-A). In fact, a placebo-controlled study of pantethine in healthy North American subjects published in 2011 found that after 16 weeks of daily use (weeks 1-8 = 600 mg/ day, weeks 9-16 = 900 mg/day) there were significant benefits to cholesterol parameters, including apolipoprotein B.

 

Detoxification & the Liver

 

Acetylation reactions and acetyl-CoA play important biochemical roles beyond energy production in the body.  As one example, acetylation is a common tool of detoxification machinery that helps metabolize toxins, pollutants, and drug metabolites (collectively: xenobiotics) so they can be more readily excreted from the body. Acetylation is often involved in post Phase II detoxification, allowing further modification of the metabolite for ready disposal.  One example of this is the fate of glutathione conjugates (common phase II products) that become acetylcysteine conjugates prior to elimination.   First, the glycine and glutamate amino acid residues are removed from what was the glutathione molecule, leaving the cysteine residue exposed.  At this point, the cysteine residue is acetylated and only then can the whole molecule be excreted. 

 

Adrenals & Stress Pantothenic acid has long been touted as an anti-stress vitamin necessary for proper adrenal functioning.  This claim for pantothenic acid rests primarily upon its role in adrenal hormone production, but unfortunately has little clinical trial evidence in support.  However, human trials have shown a positive influence on some indicators of adrenal function.  For example, when 20 subjects with elevated stress were given pantethine in a specially designed test, analysis of their urine indicated an improvement in adrenal response.

 

No product offered for sale is intended to diagnose, treat, cure or prevent any disease. You should always seek advice from your professional healthcare provider before taking any medication. Always read the details and instructions on the label, keep the tub tightly sealed and out of the reach of children.

About This Site

The BigVits site was created by experts who were given a simple brief: Make shopping with BigVits an easy and enjoyable experience, make it easy to navigate and forgiving to mistakes.

Be assured, the BigVits site is totally secure. When it comes to payment, for just a few seconds, you are transferred to the credit card people. They take your details and then hand you back to At no time do BigVits see more than the last 4 digits of you credit card number.

As you become more familiar with the site, you will discover many helpful features. For example, you can save any number of favourites lists which you can name yourself, "Gran's Joints", "Dad's Cholesterol" or "Daily Vits for the family" . These can then be picked up, modified if required and - one click re-ordered.

Don't hesitate to experiment, you can't do any damage and for security, you will always be asked to confirm your identity before your order is placed.

Members Sign Up

Have you registered to save time and get special membership offers? Click here, it only takes a couple of minutes.

Members Sign Up

Have you registered to save time and get special membership offers? Visit our desktop website, it only takes a couple of minutes.

Best Prices

Special offers every day with We won't be beaten for service and price.

Dispatch Centres

All tax paid and legally imported into the two BigVits Dispatch Centres in the UK.

Now Authorised PremierVits HOG Authorised HOG Authorised JARROW Authorised Source Naturals Authorised
Go to the top of this page
SSL Certificate from Comodo