healthy living through science & education
Why B12 Is Important
Methylcobalamin (methyl B12) is the most bioavailable and best utilized form of vitamin B12. Methyl B12 is more effective than traditional forms of B12. Methyl B12 is well retained and is active without the need for conversion by the body unlike other forms.
Clinical studies have documented methyl B12 efficacy in slowing the effects of aging on nerve tissue. Methyl B12 also appears to help balance brain chemicals and promote neurotransmitter synthesis to improve communication between nerve cells. Studies also demonstrate B12s ability to reduce high blood homocysteine levels, a pro - oxidant marker that has been linked to arterial injury and other health concerns.
Methyl B12 may also help with irregular sleep patterns, immune function and promoting normal cell growth. Finally, Methyl B12 plays a strategic role in the production of oxygen carrying blood cells.
Methyl B12 Is The Superior Form of Vitamin B12
Methyl B12, as the active coenzyme form of the vitamin, possesses numerous distinct advantages over the other forms of this nutrient.
Methyl B12 is excreted in urine at about one third that of cyanocobalamin (the most common form in vitamin supplements), indicating substantial tissue retention.
Enhanced Neurological Activity
Only methyl B12 initiates methylation, a process where methyl (CH3) groups are donated to the myelin sheath that insulates nerve fibers and regenerates neurons. Methyl B12 also helps synthesize neurotransmitters (e.g., serotonin, dopamine, norepinephrine).
Reduced Homocysteine Levels
Methyl B12 is a catalyst for the conversion of homocysteine to methionine, an essential amino acid. It also helps remove other toxins (e.g., arsenic) from the body.
Highlights of current research:
Methyl B12 has been shown to prevent brain degradation from glutamate, aspartate, and nitroprusside induced cell toxicity.
Methyl B12s protection against glutamate induced toxicity complements L dopa supporting regimens. Clinical studies have administered large amounts of methyl B12 to Alzheimers patients as a nutritional aid. Patients exhibited better cognitive functions (e.g., memory, mood, social interaction) when their levels of methylated B12 were improved, which is reflective of enhanced neurotransmitter production.
Methyl B12 supports nerve function by contributing to nerve myelination. It has also been shown to stimulate protein synthesis for repair and neural regeneration.
Irregular Cell Growth
Administration of methyl B12 has been shown to facilitate normal cell division in mice.
A clinical study showed that methyl B12 improved T cell activity
(i.e., cell-mediated immunity).
Methyl B12 supports better 24-hour sleep patterns by raising melatonin (the sleep hormone) earlier in the evening to induce sleep, and decreasing it earlier in the morning to make waking easier.
A double blind controlled study showed that high doses of methyl B12 significantly increased muscle action potential.
Risk Factors for Vitamin B12 Deficiency
Advancing age, medication, and diet are the primary risk factors for vitamin B12 deficiency. It is recommended that people over fifty consider supplements and vitamin B12 fortified foods. Indeed, up to 40 percent of older individuals suffer from reduced stomach acid, which impairs absorption of protein bound vitamin B12. Medications for stomach ulcers, heartburn, or GERD inhibit gastric secretions, and impair vitamin B12 absorption. Any disorder of the digestive tract may increase the risk for vitamin B12 deficiency.
Diet is a major risk factor for vitamin B12 deficiency. The best sources of vitamin B12 are animal products, such as meat, eggs, and fish. Therefore, strict vegetarians (those who eat no animal products) are at considerable risk. One study reported vitamin B12 deficiency in 58% of vegetarians.
Most Bioavailable Form of B12 with Superior Tissue Retention
Reduces Levels of Toxic Homocysteine
Assists in Nerve Cell Regeneration
Supports the Production of Neurotransmitters Important for Energy and Mood
No product offered for sale is intended to diagnose, treat, cure or prevent any disease. You should always seek advice from your professional healthcare provider before taking any medication. Always read the details and instructions on the label, keep the tub tightly sealed and out of the reach of children.